Plaque Psoriasis | UCB Medical Affairs

The power and pain behind the plaques

The complex immunopathogenic mechanisms driving plaque psoriasis (PSO) involve interactions between keratinocytes and immune cells, overloading the cycle of inflammation that keeps patients plugged into their psoriasis—bound by skin plaques causing clinical symptoms of pain, itching, and burning sensations.^1,2

Learn more at LightsOutPSO.com

References

Strober BE, van der Walt JM, Armstrong AW, et al. Clinical goals and barriers to effective psoriasis care. Dermatol Ther (Heidelb). 2019;9(1):5-18.
Pfaff CM, Marquardt Y, Fietkau K, Baron JM, Lüscher B. The psoriasis-associated IL-17A induces and cooperates with IL-36 cytokines to control keratinocyte differentiation and function. Sci Rep. 2017;7(1):15631.

Mapping the landscape ofinflammation in moderate-to-severe

plaquepsoriasis

The power and pain behind the plaques

References

Mapping the landscape of
inflammation in moderate-to-severe

plaque
psoriasis